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No build-up of tolerance (loss of biological sensitivity to the compound) has been reported from repeated or continued use from huperzine A, at least according to one early study [38]

fragilis collected in Maine, USA

Clin Chem (2003) 49(2):295302.10.1373/49.2.295 92 ZhuYZhuR-XHeZ-YLiuXLiuH-N
