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However, this in vitro observation may not be valid for the brain in vivo , and in glutamate-dehydrogenase knock-out mice glutamate oxidation, determined in astrocyte cultures is reduced, but absolutely not abolished (Frigerio et al., 2011
This makes oral administration an interesting choice for those dealing with stress-induced GI dysfunction or inflammatory bowel conditions linked to mood disorders
Endocrinology 142 : 51825189 Hollenga C et al
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