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Furthermore, it has been shown that 2472 hour zero-calorie fasting causes liver mitochondrial oxidative stress in rats by increasing mitochondrial free radical leak and reactive oxygen species (ROS) generation at complex III level in vivo studies [45, 46]

Miyamoto A, Wakabayashi H, Watanabe A

This was attributed to the fact that the subjects used had been involved in swim training for at least 16 weeks and were at the capacity of their physiological limits
