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Figure 36 shows that at different dosing intervals, the concentration-time curves will have different maximum and minimum values even though the average concentration will always be 10 mg/L

TLR4 also activates the TIR base containing adaptor-inducing interferon- (TRIF) located on the endosome [70]

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However, it should be noted that this concentration may not take into account protein-bound copper, and indeed, later experiments using a fluorescent probe along with ICP-MS found that following depolarization the concentration of free copper released from synaptosomes was likely to be closer to 23 M (Hopt et al., 2003)