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Description
Doxorubicin generates oxidative stress, damages mitochondria in heart cells, and triggers apoptosis (programmed cell death)
NF-B (p50 and p65) is then translocated into the nucleus where it binds to specific sequences of DNA to cause an inflammatory response
Metformin, though not a GLP-1 agonist, shares the property of reducing stomach acid and interfering with b12 absorption
Taking a sound sleep of at least 8 hours at night also helps
