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In: CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS & Neurological Disorders), 15(1), pp

196,199 Management strategies include intensive glycemic control to potentially slow cognitive decline, as well as lifestyle interventions to support cognitive health

The review traced foundational work demonstrating that protein glutathionylation occurs in response to both oxidative stress and hormonal stimulation, confirming it as a major mechanism of redox-regulated signal transduction

"Effect of N-acetylcysteine on glycemic and oxidative stress markers in type 2 diabetic patients." J Diabetes Metab Disord
