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A study investigated the possible pathway by which H 2 O 2 induced apoptosis in glioma cells and concluded that oxidative stress inhibited glioma cell growth and induced apoptosis via a caspase-3-dependent pathway (Liu et al., 2015)
Until today, there are many small molecule blockers of TRPV1 (AZD1386) (Clinical Trials, 2014), that have been tested in clinical trials of several NP conditions
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