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increased glutathione in acute myeloid leukemia Ferritin Leukemia: Not Only a Marker of Inflammation and Iron Overload, but Also a Regulator of Cellular Iron Metabolism, Signaling and Communication Mitochondrial metabolism as a target

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The fold change in the gene expression level between the sham and UUO samples was estimated using the GFOLD algorithm 38

increased glutathione in acute myeloid leukemia Ferritin Leukemia: Not Only a Marker of Inflammation and Iron Overload, but Also a Regulator of Cellular Iron Metabolism, Signaling and Communication Mitochondrial metabolism as a target

doi:10.1002/cmmi.146 Tseng MT et al (2014) Persistent hepatic structural alterations following nanoceria vascular infusion in the rat

increased glutathione in acute myeloid leukemia Ferritin Leukemia: Not Only a Marker of Inflammation and Iron Overload, but Also a Regulator of Cellular Iron Metabolism, Signaling and Communication Mitochondrial metabolism as a target

Future preclinical work may probe combinations with incretin-based agents or -oxidation enhancers to define mechanistic complementarity

increased glutathione in acute myeloid leukemia Ferritin Leukemia: Not Only a Marker of Inflammation and Iron Overload, but Also a Regulator of Cellular Iron Metabolism, Signaling and Communication Mitochondrial metabolism as a target

These effects were markedly attenuated by Se supplementation, as compared to the control group (Figure 1B)

increased glutathione in acute myeloid leukemia Ferritin Leukemia: Not Only a Marker of Inflammation and Iron Overload, but Also a Regulator of Cellular Iron Metabolism, Signaling and Communication Mitochondrial metabolism as a target

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