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Description
Considering the results of the previous studies, it is possible to outline a hypothesis about the involvement of cannabinoids in the HPA axis and subsequent regulation of the P450 enzymes (see Figure 1 below)

However, remember that these effects wont last forever, and youll want to make the most of your new-found pain relief

Leukemia 11(12):2039-44, 1997

While they seem to work in test animals fed extreme doses, this has no relevance to the doses commonly recommended in humans