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Description
This injury disrupts the brain's normal communication pathways and can cause significant neurological deficits


Pharmacokinetics of superselective intra-arterial and intravenous [11C]BCNU evaluated by PET

Additionally, GBM maintains an immunosuppressive local microenvironment through a variety of signaling pathways, including the release of immunosuppressive cytokines (e.g., IL-6), the expression of immune checkpoint molecules (e.g., PD-L1), TGF-B signaling, and the expression of STAT3 [25,26,27,28,29,30]
