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116,117 ARNTL2 is highly expressed in patients with lung adenocarcinoma and has been shown to be an independent predictor of poor prognosis in these patients

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Hepatocyte growth factor-induced c-Src-phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway inhibits dendritic cell activation by blocking IB kinase activity

however, the biological and clinical significance of this finding remains unknown
