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Some of the polypeptides can be antifibrotic, anti-inflammatory, inhibit abnormal angiogenesis, improve apoptosis, and reduce renal vascular leakage

In yet another example, an engineered GPCR may be capable of being activated with less than all of the regulatory factors and/or conditions typically required for GPCR activation (e.g., ligand binding, phosphorylation, conformational changes, etc.)

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