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Effects of 12-month, double-blind N-acetyl cysteine on symptoms, cognition and brain morphology in early phase schizophrenia spectrum disorders

Introduction Schizophrenia is a severely debilitating disorder with a suspected lifetime prevalence of 0.7% and an average age of onset between 16 and 30 years (Zheng et al., 2018

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These results indicated that H 2 O 2 initiated more p53 nuclear translocation and intensified the nuclear p53progerin interaction, which broke by overexpression of IGF-1 with adenovirus vector
