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Treatment of large CT26 colon cancer tumors (1000 mm 3 ), with a volume known to be refractory to immune checkpoint therapy (ICT), with vitamin C in combination with the ICTs anti-CTLA-4 and anti-PD-1 led to tumor regression
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No significant differences with respect to l-2HG production by strain HPGluA2 with different oxygen supply were observed (Figure 7)

GLO I finds itself entwined in the pathogenesis of these disorders
