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Notably, thioredoxin reductase (TrxR) can reduce oxidized forms of glutaredoxins (Grx) and GPx, both of which depend on GSH for their redox activity [44]
175-181 The finding that the administration of all-trans retinoic acid (ATRA) in elastase-induced emphysema in rats reversed the emphysematous changes, 182 suggested that ATRA might be a beneficial therapy for patients with emphysema
J Psychiatr Res 45:13581365

Theyre important for the prevention of brain and spinal cord birth defects