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They can be used alone or combined with PRP to enhance tendon repair

The patient was noted to have profound peripheral and central cyanosis, as well as chocolate colored arterial blood

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In adults and older children, the total volume used should also stay within safe limits animal studies suggest up to about 30 mL (the full vial) can be given to an adult without benzyl-alcohol toxicity, but one should still use only the amount needed and discard the rest if sterility is lost