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doi: 10.3390/ijerph15112371 96 GuoQ.LehmerC.Martnez-SnchezA.RudackT.BeckF.HartmannH.et al
Structure and mechanism of ABC transporters
Such damage disrupts the ability of neurons to transmit nerve impulses, resulting in a widespread of disease manifestation and numerous symptoms including physical, sensorial, cognitive, and sometimes psychiatric problems (Miller et al., 2005)
As aquaporin-4 is mainly localized in the astrocyte endfeet, these are the primarily affected cells in this disease
