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The activation of microglia is regulated by pattern recognition receptors (PRRs), including Toll-like receptors (TLRs) and nucleotide-binding and oligomerization domain (NOD)-like receptors (NLRs), which can recognize pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) (Lopez Rodriguez et al., 2021

In a Danish cohort of patients with inflammatory bowel disease receiving infliximab, infusion reactions were most strongly associated with younger patients and with episodic therapy

The study concluded that the exact mechanism of action for efficacy was not fully determined

Thymosin beta 4 alleviates non-alcoholic fatty liver by inhibiting ferroptosis via up-regulation of GPX4