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Small molecule inhibition of gut microbial choline trimethylamine lyase activity alters host cholesterol and bile acid metabolism

These observations indicate that d 9 -l-carnitine production from oral d 9 -BB occurs via a mechanism that is not suppressed by antibiotics, and are consistent with expected results from the endogenous l-carnitine biosynthetic pathway (i.e., host conversion of BB to l-carnitine during carnitine biosynthesis) (3234)

Numerous studies have shown that l-carnitine administration can improve or prevent liver damage due to various insults by ameliorating hepatic mitochondria -oxidation and reducing oxidative stress

Mitochondrial decay in the brains of old rats: ameliorating effect of alpha-lipoic acid and acetyl-L-carnitine