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Signs and Symptoms of Vitamin B12 Deficiency Early symptoms: Weakness and fatigue Pale skin Headaches Mild mood changes Intermediate symptoms: Tingling or numbness in hands and feet Breathlessness Heart palpitations Mouth ulcers or a red, swollen tongue (early to intermediate signs) Advanced symptoms: Memory problems Depression, anxiety, mood swings Poor balance or coordination Weight loss, poor appetite Constipation or loose motions Visual disturbances In some cases, long-term deficiency can cause permanent nerve damage , so early detection is key

For many people, the challenge is not just getting started

It is posited to be involved in several cellular processes, including the regulation of immune responses and wound healing

Acute gallbladder disease events, such as cholecystitis or cholelithiasis, have been reported in clinical studies