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Furthermore, it showed that HDAC2, as a predominant regulator, is recruited to the Prckd gene and removes H3K9 acetylation, resulting in repression of Prckd expression

Abstract Ferroptosis is an iron-dependent form of regulated cell death driven by lipid peroxidation and glutathione (GSH) depletion and represents a therapeutic vulnerability in hepatocellular carcinoma (HCC)

Gynecologic Oncology , 131 (2), 357361

Recent research indicates lipid and amino acid metabolism provides a foundation for ferroptosis