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Description
LC-MS/MS, liquid chromatography-tandem mass spectrometry

It can be assumed that this result was rather caused by the high individual variation at the beginning of the trial

Mitochondrial areas (m 2 ) were quantified in an investigator-blinded manner in 20 microscopic fields containing 2436 mitochondria (vehicle hearts) and 24 microscopic fields containing 1879 mitochondria (METH hearts) to calculate the average mitochondrial size and determine the number of mitochondria per microscopic field using NIH ImageJ (v1.6.0) software 32
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