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However, when bleeding finally does occur, it's often heavier because the uterine lining has built up unchecked due to unopposed estrogen, she explains

These channels, such as Piezo1 and Piezo2, respond to mechanical stimuli by allowing ions to flow into cells, triggering downstream signaling pathways that regulate cellular responses to mechanical stress

10.1186/s41983-022-00452-2 Egypt J Neurol Psychiatry Neurosurg

This method bypasses the digestive system, delivering the medication directly into the bloodstream, usually providing faster relief
