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Im Krper wird es aus den Aminosuren Glutaminsure, Cystein und Glycin gebildet

2 (1987): 119134, 10.1089/CNS.1987.4.119

It then systematically details the specific mechanistic architectures that define each pain subtype, explaining how tissue injury, nerve damage, and maladaptive central processing translate into unique clinical experiences (Figure 2)

Systemic and topical administration work through different pathways, potentially complementing each other