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La tcnica consiste en que las molculas de gran tamao no penetran por los poros del polmero, por lo que migran mucho ms rpidamente que las de menor tamao que s son capaces de penetrar por los poros de la matriz

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A reduction in the expression of PINK1 was demonstrated to result in a significant decline in the function of the mitochondrial electron transport chain (ETC) as well as the mtDNA copy number in hepatocellular carcinoma cell lines, as evidenced in a study (Kung-Chun et al., 2019)