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This dual-action mechanismsupplying the fuel via L-Carnitine and accelerating the engine via fumarateis particularly beneficial for combating post-exertional malaise (PEM)
To illustrate the systemic regulation of nutritional metabolism by L-carnitine in zebrafish, the interaction of different metabolic pathways in the L-carnitine-fed fish is shown in Fig
Dialysis-associated carnitine deficit, in turn, has been linked to a number of symptoms seen in uremic patients, including fatigability, cardiomyopathy, anemia, and skeletal muscle weakness (Eknoyan et al., 2003)
