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Interestingly, a 2014 study by Kuper, et al
Thus, in acute HIV-1 infection, RNS may inhibit viral replication

However, if a viral onslaught occurs and the cells run out of available Langerin, these cells become viral transporters for infection and deliver the virus to lymph nodes

doi: 10.1016/j.freeradbiomed.2009.09.026