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Similarly, the direct annual costs associated with BPS rose from $481 million to $750 million (amounts standardized to 1996-1998 values)

However, most supporting evidence currently arises from observational associations and mechanistic models in rodents or small human cohorts, and causal links in large human populations remain under active investigation [69]

Unexpected shortages, delayed shipments, and inconsistent sourcing can disrupt projects and create unnecessary administrative burdens

Kohda, M
