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In a more recent study, we confirmed chronic HIF-1 stabilization in DBA/2 J mice could induce a pseudohypoxic state and, by doing so, promote hypoxia-induced mitophagy through elevated protein levels of BNIP3 (Nsiah et al., 2023)

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doi: 10.1039/d3fo00797a [DOI] [PubMed] [Google Scholar] 33.Grenham S, Clarke G, Cryan JF, Dinan TG