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It is also typically avoided in patients who have recently had a heart attack, because arginine supplementation was associated with worse outcomes in that setting

Unlike NAD+ precursors, researchers study 5-Amino-1MQ mainly for how it interacts with the NNMT enzyme

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**Lower cost** AOD-9604 was historically cheaper than GLP-1 medications However, the clinical reality is that AOD-9604 failed its pivotal weight loss trial
