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Description
In the T-cell dependent pathway, ADAs are generated when a T helper cell (Th) differentiates into a Th1 or Th2 phenotype and, following their cognate interactions with B cells, induces the proliferation of plasma cells (PC) that secrete ADAs

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[DOI] [PubMed] [Google Scholar] 175.Liapis A.I., Bruttini R

Genetic polymorphisms may be a contributing factor as to why its hard to precisely pin down a healthy MMA threshold
