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doi: 10.1111/jpn.12871 11

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Conversely, the HIF-1 inhibitor 2ME2 effectively promotes osteoclast ferroptosis and prevents ovariectomy-induced OP in rats (103) that the expression of NADPH oxidase 4 (NOX4) is elevated in OP mice and patients, and NOX4 overexpression drives osteoblast ferroptosis and subsequently causes bone loss in OP mice

Reprintpreferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
