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Under normal physiological conditions, uptake of oxLDL by macrophages is probably generally protective, because subsequent efflux of the cholesterol from the macrophages to HDL via reverse cholesterol transport as well as emigration of these macrophages from the arterial wall to lymph nodes serves to minimize the accumulation of cholesterol-laden macrophages in the arterial wall

Impact of TMAO on DCs DCs, as the most potent professional antigen-presenting cells in the body, play a pivotal role in antigen recognition and signal transmission during immune response

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The simultaneous inhibition of AVP receptors 1 and 2 abolished the AVP-induced elevation of blood pressure, whereas blocking each receptor alone resulted in the insufficient normalization of blood pressure in mid- and late-pregnancy (247)