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Both paclitaxel and docetaxel are extensively metabolized, via cytochrome P 2C8 and 3A4, respectively, albeit pharmacological activity of these metabolites is modest at best and their contribution to the development of CIPN is unknown

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[DOI] [PubMed] [Google Scholar] Yu AC, Schousboe A, Hertz L

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S., Catherino W

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FOS = Fructooligosaccharides

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