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Math shown: Concentration in mcg/mL = total compound in mcg divided by water volume in mL

Natriuretic Peptides Atrial Natriuretic Peptide (ANP) and B-type natriuretic peptide (BNP), the main natriuresis hormones, are synthesized in cardiac tissue in response to stretching that occurs with increases in blood volume and function to decrease extracellular fluid volume and increase renal sodium excretion (108)

Lots of rat studies