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After 8 weeks of treatment period, the addition of Astragalus decoction significantly reduced scores on the Unified Parkinsons Disease Rating Scale (UPDRS) Part III and the Parkinsons Disease Quality of Life Questionnaire (PDQ-39) compared to levodopa monotherapy
doi: 10.1016/j.ajpath.2011.01.036
The importance of ECM cleavage in this process is evident from the phenotype of mice lacking metalloproteinases: a lack of MMP11 leads to a decreased periductal collagen content and decreased mammary gland morphogenesis 63
doi: 10.1016/j.apsb.2020.10.007
