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The gene dosage hypothesis states that the increased dosage of Chr21 genes is the direct cause of the phenotypical alterations of the DS population

In this study, we focused on the mechanism of tumor-induced neutrophil function in the tumor-bone microenvironment

examined the relationship between vitamin B and glaucoma in the US population and found that increased intake of vitamin B6 was negatively associated with the risk of glaucoma (14), providing new evidence for the potential role of vitamin B6 in glaucoma prevention

The latter is consistent with the well-known beneficial effect of MSCs on articular chondrocytes [40]