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Crosstalk between Autophagy and Type I Interferon Responses in Innate Antiviral Immunity
The anti-inflammatory response is mediated by neuroendocrine and parasympathetic pathways that down regulate TNF and IL-6 [134]
However, functional defects in N-myristoyltransferase (NMT) within T cells of RA patients impede AMPK activation, leading to hyperactivation of the mTORC1 pathway and encourages the proliferation of Th1 and Th17 cells (154)
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