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Glucocorticoid sensitivity in health and disease

For a cardiovascular performance assay, six endpoints were chosen to evaluate the cardiovascular performance in the zebrafish larvae: the heart rate and time interval in ventricles, stroke volume, cardiac output, ejection fraction, and shortening fraction

Treatment with L-Cys reduced the accumulation of CD11b + /CD45 high cells, the activation of microglia and astrocytes, and the increase in ROS and MDA within the injured cortex

Activation of NF-k antagonizes programmed cell death induced by TNFR1, and GSH depletion has been shown to down-regulate TNF-induced NF-k activation and sensitize to apoptotic cell death [123]