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Silibinin suppresses glioblastoma cell growth, invasion, stemness, and glutamine metabolism by YY1/SLC1A5 pathway
Copper also plays a role in mediating the interaction between HIF-1 and HRE to initiate the expression of copper-dependent genes such as VEGF (49)

Despite significant advances in mechanical treatments such as rotational atherectomy, these methods are passive treatments for advanced calcification (191)
