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Disruption of the normal gut microbiota may lead to intestinal dysbiosis, barrier dysfunction, bacterial translocation, and excessive production of uremic toxins, including indoxyl sulfate (IS), p-cresyl sulfate (p-CS), and trimethylamine-N-oxide (TMAO), all of which are implicated in the variant processes of kidney diseases development (Chen et al., 2019)

Control groups received scopolamine or aCSF 20 min prior to testing followed by aCSF 10 min prior testing

Adipose tissue modulates homeostatic functions in both adipose and multiple non-adipose organs through the secretion of diverse bioactive molecules, collectively termed adipokines [219]
