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doi: 10.3389/fimmu.2018.00365
The main function of granulosa cells, relevant to oocyte development and ovarian functions, is steroidogenesis, for which different signaling pathways, including Jak/STAT, PI3K/Akt, and pro-MAPK/ERK1/2, regulate this fundamental process, all of which have a shared modulator named IGF
10.1 Male 10.1.1 In vivo human studies The percentage of infertile men ranges from 2.5-12% depending on the studied population (289)
GenJet In Vitro DNA Transfection Reagent and buffer were purchased from Tebu-bio (Heerhugowaard, Netherlands)
