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All animal experiments were conducted in accordance with the approved guidelines and the National Institutes of Health (NIH) Guide for the care and use of laboratory animals

Overexpression of the TXN1 ( C32S/C35S ) gene (mutant Trx1 lacking the disulfide reductase activity because of Cys32 and Cys35 substitution with serine) in HeLa cells promoted nitrosylation of specific target proteins

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