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Nephrol Dial Transplant 23:991997 Mantovani G, Macci A, Madeddu C, Gramignano G, Serpe R, Massa E, Dess M, Tanca FM, Sanna E, Deiana L, Panzone F, Contu P, Floris C (2008) Randomized phase III clinical trial of five different arms of treatment for patients with cancer cachexia: interim results
Ischemic glutamate receptor hyperactivation stimulates phosphatidylinositol-specific PLC, cleaving PIP 2 into IP 3 and diacylglycerol (DAG)
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One way is that the buildup of CYP in the testicles could have harmed the Sertoli cells directly, resulting in impaired spermatogenesis and fewer sperm
