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Transcription initiation requires nucleosome displacement at promoter regions to expose regulatory elements, allowing transcription factor binding and recruitment of RNA polymerase (74, 151)

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This differential regulation allows therapeutic benefits without common side effects associated with NO manipulation

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Schwartzentruber, J

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Curr Pharm Des 17(16):16121632 Sikiric P, Seiwerth S, Rucman R, Turkovic B, Rokotov DS, Brcic L et al (2012) Focus on ulcerative colitis: stable gastric pentadecapeptide BPC 157

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