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Reference: Gwyer D, Wragg NM, Wilson SL (2019)
Small-molecule inhibitors of copper chaperone proteins The clinical use of copper ion chelators often leads to low copper ion concentrations, resulting in serious toxic side effects that disrupt other normal physiologic processes that require copper ions
The persistently high mortality rate suggests a need for novel therapeutic interventions to improve survival, requiring thorough understanding of sepsis pathophysiology (17)
