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the decrease in HGF-dependent MDCK proliferation below control levels for some compounds is not surprising since the experiment was earned in 2% serum, which likely contains some level of HGF

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Pediatr Nephrol 13(9):865869 Roelfsema V, Clark RG (2001) The growth hormone and insulin-like growth factor axis: its manipulation for the benefit of growth disorders in renal failure

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