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Longevity and cellular health research explores how endogenous protective systems decline with age and how this decline affects tissue function
Folate, particularly methylfolate, can worsen this by further increasing SERT and dopamine transporter (DERT) activity, potentially leading to increased anxiety, OCD-like symptoms, emotional instability, and cognitive rigidity

Its decades-long use in human anti-aging and cosmetic products due to its safety and efficacy

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