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Description
We found that lactate, taken up and oxidized by the mitochondrial cluster of differentiation 147 (CD147)/monocarboxylate transporter 1 (MCT1)/lactate dehydrogenase B (LDHB) complex, was converted into the tricarboxylic acid (TCA) cycle intermediate -ketoglutaric acid (-KG), which subsequently induced MIC stemness potentials via DNA methyltransferase 3 beta (DNMT3B)-mediated SOX2 hypomethylation
Environ Sci Technol (2013) 47:82935
This thin monolayer of endothelial cells in all vessels is oriented in the direction of blood flow and synthesizes the components of the glycocalyx
McCommis and Baines, 2012
