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Theyre often temporary but can cause discomfort

[DOI] [PubMed] [Google Scholar] 286.Nimse D.P

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For cells that are cycling, the presence of TET-mediated oxidation marks on one strand of CpG dinucleotides can promote passive DNA demethylation by preventing the methylation of the CpG on the opposite strand by DNMT1 after DNA replication, ( de novo methylation by DNMT3s during development
